Hitting ‘Reset’ in Protein Synthesis Restores Myelination

Neuroscientists at UB’s Hunter James Kelly Research Institute show how turning down synthesis of a protein improves nerve, muscle function in common neuropathy. A potential new treatment strategy for patients with Charcot-Marie-Tooth disease is on the horizon, thanks to research by neuroscientists now at the University at Buffalo’s Hunter James … Seguir leyendo / Continue reading


Vaccine Development to Treat Alzheimer’s Disease Neuropathology

A novel vaccine addressing the major hallmarks of Alzheimer’s disease (AD), senile plaque-like deposits of amyloid beta-protein (Aβ), neurofibrillary tangle-like structures, and glial proinflammatory cytokines, has been developed. The present vaccine takes a new approach to circumvent failures of previous ones tested in mice and humans, including the Elan-Wyeth vaccine … Seguir leyendo / Continue reading

Risk Genes for Alzheimer’s Linked to Brain Changes at Birth

Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer’s disease, schizophrenia, and autism can also be seen in the brain scans of newborns. “These results suggest that prenatal brain development may be a very important influence on psychiatric risk later in … Seguir leyendo / Continue reading